A three-range approach enhances the prognostic utility of CSF biomarkers in Alzheimer’s disease.

por jcdadm.website | mar 13, 2022 | Publication

Brum WS, de Bastiani MA, Bieger A, Therriault J, Ferrari-Souza JP, Benedet AL, Saha-Chaudhuri P, Souza DO, Ashton NJ, Zetterberg H, Pascoal TA, Karikari T, Blennow K, Rosa-Neto P, Zimmer ER; Alzheimer’s Disease Neuroimaging Initiative (ADNI). Alzheimers Dement...

Comparing tau status determined via plasma pTau181, pTau231 and [18F]MK6240 tau-PET.

por jcdadm.website | fev 1, 2022 | Publication

Tissot C, Therriault J, Kunach P, L Benedet A, Pascoal TA, Ashton NJ, Karikari TK, Servaes S, Lussier FZ, Chamoun M, Tudorascu DL, Stevenson J, Rahmouni N, Poltronetti NM, Pallen V, Bezgin G, Kang MS, Mathotaarachchi SS, Wang YT, Fernandez Arias J, Ferreira PCL,...

Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer’s disease.

por jcdadm.website | fev 1, 2022 | Publication

Ashton NJ, Benedet AL, Pascoal TA, Karikari TK, Lantero-Rodriguez J, Brum WS, Mathotaarachchi S, Therriault J, Savard M, Chamoun M, Stoops E, Francois C, Vanmechelen E, Gauthier S, Zimmer ER, Zetterberg H, Blennow K, Rosa-Neto P. EBioMedicine. 2022 Feb;76:103836. doi:...

Impact of long- and short-range fibre depletion on the cognitive deficits of fronto-temporal dementia.

por jcdadm.website | jan 24, 2022 | Publication

Savard M, Pascoal TA, Servaes S, Dhollander T, Iturria-Medina Y, Kang MS, Vitali P, Therriault J, Mathotaarachchi S, Benedet AL, Gauthier S, Rosa-Neto P; Frontotemporal Lobar Degeneration Neuroimaging Initiative. Elife. 2022 Jan 24;11:e73510. doi:...

Direct Comparison of the Tau PET Tracers 18F-Flortaucipir and 18F-MK-6240 in Human Subjects.

por jcdadm.website | jan 1, 2022 | Publication

Gogola A, Minhas DS, Villemagne VL, Cohen AD, Mountz JM, Pascoal TA, Laymon CM, Mason NS, Ikonomovic MD, Mathis CA, Snitz BE, Lopez OL, Klunk WE, Lopresti BJ. J Nucl Med. 2022 Jan;63(1):108-116. doi: 10.2967/jnumed.120.254961. Epub 2021 Apr 16.

Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.

por jcdadm.website | dez 16, 2021 | Publication

Pascoal TA, Benedet AL, Tudorascu DL, Therriault J, Mathotaarachchi S, Savard M, Lussier FZ, Tissot C, Chamoun M, Kang MS, Stevenson J, Massarweh G, Guiot MC, Soucy JP, Gauthier S, Rosa-Neto P. Brain. 2021 Dec 16;144(11):3517-3528. doi:...

Pitt Psychiatry Faculty Members Invited to Contribute to World Alzheimer Report 

por Fernando Rigon | dez 13, 2021 | News

In fall 2021, Alzheimer’s Disease International published World Alzheimer Report 2021: Journey though the diagnosis of dementia, a compendium of research on the disease, currently the seventh leading cause of mortality worldwide. The report addresses numerous...

Soluble amyloid-beta isoforms predict downstream Alzheimer’s disease pathology.

por jcdadm.website | dez 11, 2021 | Publication

Povala G, Bellaver B, De Bastiani MA, Brum WS, Ferreira PCL, Bieger A, Pascoal TA, Benedet AL, Souza DO, Araujo RM, Zatt B, Rosa-Neto P, Zimmer ER; for the Alzheimer’s Disease Neuroimaging Initiative. Cell Biosci. 2021 Dec 11;11(1):204. doi:...

Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum.

por jcdadm.website | dez 1, 2021 | Publication

Benedet AL, Milà-Alomà M, Vrillon A, Ashton NJ, Pascoal TA, Lussier F, Karikari TK, Hourregue C, Cognat E, Dumurgier J, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, Salvadó G, Shekari M, Operto G, Gispert JD, Minguillon C, Fauria K, Kollmorgen G, Suridjan I,...

Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal fluid.

por jcdadm.website | nov 15, 2021 | Publication

Gobom J, Parnetti L, Rosa-Neto P, Vyhnalek M, Gauthier S, Cataldi S, Lerch O, Laczo J, Cechova K, Clarin M, Benet AL, Pascoal TA, Rahmouni N, Vandijck M, Huyck E, Le Bastard N, Stevenson J, Chamoun M, Alcolea D, Lleó A, Andreasson U, Verbeek MM, Bellomo G, Rinaldi R,...